Dendritic cells, but not macrophages or B cells, activate major histocompatibility complex class II‐restricted CD4+ T cells upon immune‐complex uptake in vivo
JMH De Jong, DH Schuurhuis, A Ioan‐Facsinay… - …, 2006 - Wiley Online Library
Professional antigen‐presenting cells (APC) are able to process and present exogenous
antigen leading to the activation of T cells. Antigen–immunoglobulin (Ig) G complexes (IC)
are much more efficiently processed and presented than soluble antigen. Dendritic cells
(DC) are known for their ability to take up and process immune complex (IC) via FcγR, and
they have been shown to play a crucial role in IC‐processing onto major histocompatibility
complex (MHC) class I as they contain a specialized cross‐presenting transport system …
antigen leading to the activation of T cells. Antigen–immunoglobulin (Ig) G complexes (IC)
are much more efficiently processed and presented than soluble antigen. Dendritic cells
(DC) are known for their ability to take up and process immune complex (IC) via FcγR, and
they have been shown to play a crucial role in IC‐processing onto major histocompatibility
complex (MHC) class I as they contain a specialized cross‐presenting transport system …
[PDF][PDF] Dendritic cells, but not macrophages or B cells, activate MHC class II-restricted CD4 T cells upon immune-complex uptake in vivo.
JMH de Jong, DH Schuurhuis… - …, 2006 - scholarlypublications …
Professional antigen-presenting cells (APC) are able to process and present exogenous
antigen leading to the activation of T cells. Antigen–immunoglobulin (Ig) G complexes (IC)
are much more efficiently processed and presented than soluble antigen. Dendritic cells
(DC) are known for their ability to take up and process immune complex (IC) via FccR, and
they have been shown to play a crucial role in IC-processing onto major histocompatibility
complex (MHC) class I as they contain a specialized crosspresenting transport system …
antigen leading to the activation of T cells. Antigen–immunoglobulin (Ig) G complexes (IC)
are much more efficiently processed and presented than soluble antigen. Dendritic cells
(DC) are known for their ability to take up and process immune complex (IC) via FccR, and
they have been shown to play a crucial role in IC-processing onto major histocompatibility
complex (MHC) class I as they contain a specialized crosspresenting transport system …
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